Journal of Orthopedics and Joint Surgery

Register      Login

VOLUME 7 , ISSUE 1 ( January-June, 2025 ) > List of Articles

CASE REPORT

A Diagnostic Dilemma: Two Case Reports of Rare Presentations of Swelling in the Medial End of Clavicle

Joseph S Pittappillil, Thyagarajan Umasankar, Raghavendran Balasubramanian, Pradeep Purushothaman, Rayeez Ahmed

Keywords : Case report, Clavicle, Medial end, Swelling

Citation Information : Pittappillil JS, Umasankar T, Balasubramanian R, Purushothaman P, Ahmed R. A Diagnostic Dilemma: Two Case Reports of Rare Presentations of Swelling in the Medial End of Clavicle. J Orth Joint Surg 2025; 7 (1):119-123.

DOI: 10.5005/jojs-10079-1178

License: CC BY-NC 4.0

Published Online: 15-01-2025

Copyright Statement:  Copyright © 2025; The Author(s).


Abstract

Aim and background: Patients presenting with swellings in the medial end of the clavicle are rare. The most common differential diagnoses include trauma and, less likely, osteomyelitis, arthritis, or neoplasms. Case description: We would like to report two cases which presented to our institute and their management, one of which was a 16-year-old boy diagnosed with Ewing sarcoma (ES) of the clavicle (nonmetastatic). The other was a 47-year-old female diagnosed with osteomyelitis of the medial end of the clavicle. The former patient received a multidisciplinary approach and underwent neoadjuvant chemotherapy, resection, adjuvant chemotherapy, and radiotherapy and had a good functional outcome. The latter underwent surgery, and appropriate culture-sensitive antibiotics were started, and the patient had a good recovery. Conclusion: Swellings in the medial end of the clavicle are rare and can have varying presentations in different age-groups, and it is important to know the possible differentials and how to manage them. Clinical significance: Patients with comparable presentations may have very different diagnoses and courses of treatment; thus, it is best to have multiple differential diagnoses in mind.


PDF Share
  1. Grier HE. The Ewing family of tumors. Ewing's sarcoma and primitive neuroectodermal tumors. Pediatr Clin North Am 1997;44(4):991–1004. DOI: 10.1016/s0031-3955(05)70541-1
  2. Gulia A, Puri A, Gupta S, et al. Functional and oncological outcomes of multidisciplinary management of Ewing's sarcoma of clavicle: a single-center experience. South Asian J Cancer 2021;10(3):138–143. DOI: 10.1055/s-0041-1731901
  3. Gerscovich EO, Greenspan A. Osteomyelitis of the clavicle: clinical, radiologic, and bacteriologic findings in ten patients. Skeletal Radiol 1994;23(3):205–210. DOI: 10.1007/BF00197463
  4. Rodriguez Martin J, Pretell Mazzini J, Viña Fernandez R, et al. Ewing sarcoma of clavicle in children: report of 5 cases. J Pediatr Hematol Oncol 2009;31(11):820–824. DOI: 10.1097/MPH.0b013e3181b7896f
  5. Eliazer S, Spencer J, Ye D, et al. Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma. Mol Cell Biol 2003;23:482–492. DOI: 10.1128/MCB.23.2.482-492.2003
  6. Ginsberg JP, Woo SY, Johnson ME, et al. Ewing's sarcoma family of tumors: Ewing's sarcoma of bone and soft tissue and the peripheral primitive neuroectodermal tumors. In: Pizzo PA, Poplack DG (Eds). Principles and Practice of Pediatric Oncology, 4th edition. Philadelphia: Lippincott Williams & Wilkins; 2002. pp. 973–1015.
  7. Ozaki T, Hillmann A, Lindner N, et al. Surgical treatment of bone sarcomas of the fibula. Analysis of 19 cases. Arch Orthop Trauma Surg 1997;116(8):475–479. DOI: 10.1007/BF00387580
  8. Wessel RN, Schaap GR. Outcome of total claviculectomy in six cases. J Shoulder Elbow Surg 2007;16:312–315. DOI: 10.1016/j.jse.2006.07.007
  9. Zhou Y, Tian Z, Yunus A, et al. A case of Ewing's sarcoma of the clavicle in adults. Int J Clin Med 2013;4:343–346. DOI: 10.4236/ijcm.2013.48060
  10. Natarajan M, Meller I, Malawer MM. Claviculectomy for tumors of the clavicle. Ind J Orthop 2006;40(2):115–118. DOI: 10.4103/0019-5413.34454
  11. Granick MS, Ramasastry SS, Goodman MA, et al. Chronic osteomyelitis of the clavicle. Plast Reconstr Surg 1989;84(1):80–84. DOI: 10.1097/00006534-198907000-00015
  12. Cierny G, Mader JT. Adult chronic osteomyelitis. Orthopedics 1984;7(10):1557–1564. DOI: 10.3928/0147-7447-19841001-07
  13. Saglam F, Saglam S, Gulabi D, et al. Bilateral clavicle osteomyelitis: a case report. Int J Surg Case Rep 2014;5(12):932–935. DOI: 10.1016/j.ijscr.2014.10.056
  14. Alessi DM, Sercarz JA, Calcaterra TC. Osteomyelitis of the clavicle. Arch Otolaryngol Head Neck Surg 1988;114(9):1000–1002. DOI: 10.1001/archotol.1988.01860210066017
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.